MOTS-c vs SS-31

MOTS-c and SS-31 are both studied in mitochondrial research but are structurally unrelated. MOTS-c is a 16-amino-acid sequence encoded in mitochondrial DNA; SS-31 is a synthetic four-residue compound containing D-arginine and 2′,6′-dimethyltyrosine.

MOTS-c and SS-31 compared
MOTS-cSS-31
CAS number1627580-64-6736992-21-5
Molecular formulaC101H152N28O22S2C32H49N9O5
Molecular weight2174.6 g/mol639.8 g/mol
Residues164
SequenceMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-ArgD-Arg-Dmt-Lys-Phe-NH2
Also listed asMOTSc, Mitochondrial ORF of the 12S rRNA type-cElamipretide, MTP-131
PubChemCID 146675088CID 11764719

MOTS-c from Biomod

MOTS-c is a 16-amino-acid sequence encoded within the mitochondrial 12S rRNA gene.

SS-31 from Biomod

SS-31 (elamipretide) is a synthetic four-residue Szeto-Schiller compound, D-Arg-Dmt-Lys-Phe-NH2, where Dmt is 2′,6′-dimethyltyrosine.

For laboratory research use only. Not for human or animal use. Biomod does not provide dosing or medical advice.